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Intraosseous Morphine Administration During Anterior Cruciate Ligament Reconstruction

Intraosseous Morphine Administration During Anterior Cruciate Ligament Reconstruction

Recruiting
18-40 years
All
Phase 4
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Overview

The purpose of this study is to determine if intraosseous (IO) morphine decreases pain and post-operative opioid use in patients undergoing anterior cruciate ligament (ACL) reconstruction.

Eligibility

Inclusion Criteria:

  • Patients of the IRB approved surgeon(s) undergoing ACL reconstruction with bone-to-bone (BTB) autograft
  • Patients aged between 18-40 years old at the time of surgery

Exclusion Criteria:

  • Patients undergoing ACL reconstruction with any other type of autograft or allograft other than BTB
  • Patients younger than 18 years old or older than 40 years old
  • Patients undergoing meniscal root repair or any other repair that changes their weight-bearing status
  • Patients with a history of substance abuse
  • Vulnerable populations
  • Patients on chronic pain medication within the last 6 months
  • BMI >/= 35
  • Allergy to morphine
  • Unwilling to participate
  • Any additional reason the PI deems reasonable

Study details
    Anterior Cruciate Ligament Tear
    Anterior Cruciate Ligament Injuries
    Anterior Cruciate Ligament Rupture

NCT06511232

The Methodist Hospital Research Institute

15 October 2025

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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