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Penile Skin Versus Buccal Mucosal Graft in Augmentation Urethroplasty for Long Anterior Urethral Stricture

Penile Skin Versus Buccal Mucosal Graft in Augmentation Urethroplasty for Long Anterior Urethral Stricture

Recruiting
18 years and older
Male
Phase N/A

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Overview

The aim of this study is to analyze the outcomes of dorsal onlay buccal mucosal graft (BMG) and penile skin graft (PSG) urethroplasty in the management of long segment bulbar urethral stricture.

Description

Penile urethral reconstruction proves to be a continuous challenge as no perfect technique is considered for all patients with this problem. Among all the methods used for treatment of urethral stricture, the substitution urethroplasty with tissue transfer using either flap or graft is the gold standard treatment option for long segment urethral strictures.

In 1993, McAninch described a circular fasciocutaneous flap for the management of penile urethral stricture up to 15 cm that showed excellent cosmetic and functional outcomes due to this being a hairless, flexible flap with a rich vascular supply.

Buccal mucosal graft (BMG) was rediscovered and popularized in 1992 by Burger et al., then El-Kassaby et al. in 1993 published a series using buccal mucosal graft to repair anterior urethral stricture. Buccal mucosal graft became an ideal urethral substitute due to easy harvesting, hairlessness and compatibility in a wet environment.

Eligibility

Inclusion Criteria:

  • Patients with long segment anterior urethral stricture that was defined as a stricture with a length of more than 1 cm with spongiofibrosis.
  • Patients with previous failed urethral dilatation or direct vision internal urethrotomy (DVIU)

Exclusion Criteria:

  • Patients with lichen sclerosus
  • Patients with history of hypospadias repair
  • Patients with recurrent urethral stricture after failed previous urethroplasty

Study details
    Penile Skin
    Buccal Mucosal Graft
    Augmentation
    Urethroplasty
    Long Anterior
    Urethral Stricture

NCT07074717

Tanta University

15 October 2025

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