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The Bone Metabolism Characteristics of Premature Ovarian Insufficiency

The Bone Metabolism Characteristics of Premature Ovarian Insufficiency

Recruiting
18-39 years
Female
Phase N/A

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Overview

Explore the bone metabolism characteristics of premature ovarian insufficiency.

Description

Explore the bone metabolism characteristics of premature ovarian insufficiency, indexes includes serum levels of TRACP-5b and BALP, BMD values of lumbar spine L1-L4, left and right hip, left and right femoral neck et.al.

Eligibility

Inclusion Criteria:

Patients diagnosed by Western medicine with premature ovarian insufficiency. 18 ≤ patients' age ≤ 39 years;. Patients who voluntarily participate in this study, sign an informed consent form.

Exclusion Criteria:

Patients with congenital gonadal dysplasia or a family history similar to "early menopause".

POI patients with acquired organic lesions or ovarian surgery. Patients who have taken Western or herbal medicine artificial cycle therapy or other endocrine therapy in the past three months.

Patients with serious primary diseases and mental disorders such as cardiovascular and cerebrovascular, liver, kidney and hematopoietic system.

Patients who are breastfeeding or pregnant.

Study details
    Premature Ovarian Insufficiency
    Bone Diseases
    Metabolic
    Bone Mineral Density

NCT06339489

Shi Yun

21 October 2025

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