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Using Three Different Doses of Hyperbaric Prilocaine 2% Local Anaesthetic ( 40,50 and 60mg ),Through Spinal Anaesthesia in Knee Arthroscopy Patients to Compare Time to Void

Using Three Different Doses of Hyperbaric Prilocaine 2% Local Anaesthetic ( 40,50 and 60mg ),Through Spinal Anaesthesia in Knee Arthroscopy Patients to Compare Time to Void

Recruiting
18-60 years
All
Phase 3

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Overview

The goal of this randomised trial is to use a short acting local anaesthetic drug (hyperbaric prilocaine 2%) which is beneficial in short operations which are performed as a day case surgery.

in this study the investigators will use 3 different doses of prilocaine 2% (40,50 or 60 mg ) intrathecal (in spinal anaesthesia) in participants undergoing arthroscopy on the knee.

the primary outcome is to compare time to micturate (go to the bathroom) between the three groups .

the secondary outcomes are:

  • time to recovery of the motor and sensory block
  • time to discharge from post anesthesia care unit
  • any complications ; itching, lowered blood pressure, nausea and vomiting.

Eligibility

Inclusion Criteria:

All patients (male/female, American Society of Anesthesiologists physical status I-II, age: 18-60 years) undergoing knee arthroscopy will be eligible for the study. -

Exclusion Criteria:

  1. Coagulopathy and other bleeding disorders (INR more than 1.4 and platelet less than 80000)
  2. Patient refusal.
  3. Infection at the site of injection.
  4. Allergies against prilocaine.
  5. Increased intracranial pressure.
  6. Severe MS and AS.
  7. Sever hypovolemia.

Study details
    Time to First Void After Spinal Anaesthesia

NCT06703580

Cairo University

21 October 2025

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