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Application of DCE-MRI Based on 4D FreeBreathing in Predicting the Efficacy of Immune and Targeted Therapy in Lung Cancer

Application of DCE-MRI Based on 4D FreeBreathing in Predicting the Efficacy of Immune and Targeted Therapy in Lung Cancer

Recruiting
18-75 years
All
Phase N/A

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Overview

This study aims to address the challenge of predicting the efficacy of targeted and immunotherapy in lung cancer patients. By utilizing two DCE-MRI images-one before treatment and one after one treatment cycle-along with the patients' clinical and pathological information, we aim to achieve accurate prediction of the therapeutic efficacy of targeted and immunotherapy in lung cancer patients.

Eligibility

Inclusion Criteria:

  1. Tumor size greater than 2 cm
  2. Age between 18 and 75 years

Exclusion Criteria:

  1. Presence of MRI contraindications (e.g., metal implants, pacemaker implantation, etc.)
  2. Allergy to gadolinium contrast agents
  3. Lesions difficult to delineate on images due to conditions such as atelectasis or diffuse lesions

Study details
    Lung Cancer

NCT06742021

Yunnan Cancer Hospital

15 October 2025

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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