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Neglect Treatment by Prism Adaptation in the Acute Phase

Neglect Treatment by Prism Adaptation in the Acute Phase

Recruiting
18-90 years
All
Phase N/A

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Overview

This project aims at unveiling the beneficial effects of prism adaptation as early rehabilitation technique to treat unilateral spatial neglect in the acute phase after a brain damage. This syndrome, frequent and very invalidating for daily life activities after a brain damage, is a cognitive disorder of lack of attention towards a part of the space. Patients at a first event brain injury hospitalized into the Neurology and Neurosurgery Departments and affected by spatial neglect will undergo to a protocol of five consecutive rehabilitation treatments, being assigned to the experimental (prisms) or control groups (neutral prisms). The effectiveness of the treatment will be assessed with cognitive, functional and motor-related measures, as well as a follow up 3 months later. These results can have a strong impact on the long-term functional outcome of these patients.

Eligibility

Inclusion Criteria:

  • First neurological event, affecting the right hemisphere or the left hemisphere (stroke, brain tumour post-surgery);
  • Structural images of the brain lesion available (magnetic resonance or tomographic scans);
  • Good Normal (or corrected) visual acuity;
  • Presence of USN, as assessed by a standard neuropsychological evaluation.

Exclusion Criteria:

  • Previous neurological disorder and/or current or previous psychiatric disease.
  • Presence or suspicion of previous general cognitive deficits documented from the clinical dossier and/or suspicious of possible cognitive deficits ;
  • Presence of difficulty in task's comprehension preventing its completion;
  • Impossibility to sustain a research session of at least 30 minutes (e.g., attentional lability).

Study details
    Unilateral Spatial Neglect

NCT06078111

University of Geneva, Switzerland

15 October 2025

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