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Effect of Different Administration Routes of Dexmedetomidine Combined with Ultrasound-Guided Fascia Iliaca Block on Emergence Agitation After Hip Replacement Surgery

Effect of Different Administration Routes of Dexmedetomidine Combined with Ultrasound-Guided Fascia Iliaca Block on Emergence Agitation After Hip Replacement Surgery

Recruiting
18-65 years
All
Phase 1

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Overview

To examine the impact of various administration routes of dexmedetomidine in conjunction with ultrasound-guided fascia iliaca block (FIB) on emergence agitation (EA) during the postoperative recovery period after hip replacement surgery.

Eligibility

Inclusion Criteria:

  1. age between 18 and 65 years, with no restriction on gender
  2. diagnosis of hip joint disease necessitating hip arthroplasty
  3. ASA grade I-II
  4. no significant cardiopulmonary, hepatic, or renal dysfunction prior to the operation
  5. no history of psychiatric disorders or long-term use of sedative medications prior to the operation
  6. signing of an informed consent form to voluntarily participate in the study.

Exclusion Criteria:

  1. patients allergic to or with contraindications to ropivacaine or dexmedetomidine
  2. patients exhibiting symptoms of agitation or delirium prior to the procedure
  3. patients with severe central or peripheral nervous system disorders
  4. patients with coagulation disorders or receiving anticoagulant therapy
  5. pregnant or breastfeeding women
  6. patients who received other medications or treatments prior to the procedure that might affect the study results
  7. patients unable to cooperate with the study or intolerant to ultrasound-guided iliofascial block

Study details
    Dexmedetomidine
    Fascia Iliaca Block

NCT06614010

Qianfoshan Hospital

15 October 2025

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