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Investigating the Effects of a Haskap Berry Supplement on Cognitive Health

Investigating the Effects of a Haskap Berry Supplement on Cognitive Health

Recruiting
50 years and older
All
Phase N/A

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Overview

This study aims to investigate the postprandial (2h) and longer term (4 week) effects of a haskap berry supplement on cognitive, vascular, and metabolic function in healthy ageing adults aged 50+.

Description

This project aims to investigate the acute benefits (during the immediate post prandial period up to 2 hours) and chronic benefits (following 4 weeks daily supplementation) of a vitamin- and mineral-enhanced haskap berry supplement made from freeze-dried, powdered haskap berries. The main objective of this study is to trial the product in older adults aged 50+ to determine any cognitive, metabolic, or cardiovascular benefits over and above haskap powder alone or a placebo powder. The study will involve a screening visit and two testing visits, 4 weeks apart. For the 24 hours prior to each test visit, participants are asked to follow a low polyphenol diet. They are requested not to consume any food or drinks except water after 8.30pm, and on the morning of test visits to only consume one slice of buttered white toast and a glass of water prior to attending the visit. During the testing visits, cognitive and mood battery tests (to include measures of memory, executive functions, and stress, will be taken at baseline, at 2 hours following the consumption of the supplement as part of a meal, and again at 4 weeks following daily consumption of the supplement added to their usual diet. Blood glucose finger pricks will be recorded at each time point along with FMD (a measure of vascular reactivity).

Eligibility

Inclusion Criteria:

  • 50+ years old
  • Fruit & veg intake less than or equal to 4 servings per day
  • Adequate English language and visual & auditory acuity to perform the cognitive tasks
  • Normal BMI for age

Exclusion Criteria:

  • Being diagnosed with psychological or psychiatric disorders
  • ADHD or dyslexia
  • Any food allergy or intolerance
  • Use of medications and dietary supplements that may impact study results
  • Antibiotic use within the last 3 months
  • Adherence to vegan or vegetarian diets, or other specific diets that may impact study outcomes
  • Conditions altering absorption of nutrients (e.g. celiac disease)
  • Being diagnosed with cardiometabolic disease (including type II diabetes and cardiovascular disease), or suffer from untreated hypertension or thrombosis related disorders
  • Taking blood thinners

Study details
    Cognition

NCT07119788

University of Reading

15 October 2025

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