Overview
The main goal of the BIocoLlection in Anorexia Nervosa-liver damage evaluation BILAN study the blood biomarkers associated with liver cytolysis.
Description
Study of the association between blood biomarkers and the presence of hepatic cytolysis, defined by AST and/or ALT above normal.
Eligibility
Inclusion Criteria :
- Patient over 15 years old
- Diagnosis of Restricted Eating Disorders including Anorexia Nervosa according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-5)
- Admission to Nantes University Hospital.
Exclusion Criteria :
- Chronic active viral hepatitis
- Hemochromatosis
- Other genetic, autoimmune.
- Treatment with a drug known to induce fatty liver disease (amiodarone, carbamazepine, tamoxifen, valproate, clozapine, anti-retrovirals) unless the dose has been stable for ≥ 3 months
- Excessive alcohol consumption (≥ 30 grams per day in men, ≥ 20 grams per day in women)
- Pregnant, parturient or breast-feeding women, persons deprived of liberty, adults under legal protection or unable to express their consent, persons not affiliated or not beneficiaries of a social security scheme, persons under guardianship or curators