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Longitudinal Endpoint Assessment of Disease Burden in HD

Longitudinal Endpoint Assessment of Disease Burden in HD

Recruiting
18 years and older
All
Phase N/A

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Overview

LEAD-HD is intended to collect and analyze self-reported health information from individuals with Huntington Disease (HD) or prodromal HD participating in a 24-month longitudinal natural history study using remote technologies.

Description

The LEAD-HD study will be offered via HSG's online observational research platform called myHDstory®. This direct to patient study will collect and analyze self-reported health information from individuals with Huntington Disease (HD) or prodromal HD in a 24-month longitudinal natural history study that participants complete at any time and with their own electronic device.

Eligibility

Inclusion Criteria:

  • Be 18 years of age or older;
  • Be willing and able to provide informed consent electronically;
  • Self-report, when answering as a participant, that you have been diagnosed with HD by a doctor, or have undergone genetic testing and been found to carry the gene mutation responsible for HD but have not been clinically diagnosed with HD (prodromal HD);
  • Have the ability to answer online questions or direct someone else to enter answers for them;
  • Have the ability to ambulate independently and take care of some of your personal needs;
  • Have the ability to read and understand English;
  • Be willing to create a unique identifier based on personal demographic information;
  • Reside in the United States or its territories. Surveys can only be completed in the US. If you move outside of the US, you will no longer be able to participate;
  • Own or have access to an electronic device and secure internet connectivity

Exclusion Criteria:

-

Study details
    Huntington Disease

NCT06475898

Huntington Study Group

15 October 2025

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