Overview
Interventions of both groups:
Oxygenated gel Group: 15 patients who used oxygenated gel (Blue®m, Wijhe, Netherlands) were trained by the co-investigator (A.H) through real demonstration for topical application of the gel on aphthous ulcers, which entails the application of 1-2 ml of oxygenated gel directly to the ulcer two times per day and this was repeated for 7 days.
Triamcinolone acetonide Group: 15 patients were treated with Kenalog in orabase (Triamcinolone acetonide 0.1% oral paste 5g), four times (i.e., at 8 am, 12 noon, 4 pm, and 8 pm) a day for 7 days at intervention group.
Patients in both groups were reexamined after treatment at different intervals (day 3, day 5, day 7, and day 10).
Eligibility
Inclusion Criteria:
- Clinically diagnosed patients with chronic aphthous stomatitis measuring ≤6 mm in size in the oral cavity and who gave written consent for participation.
- Only single ulcers were considered for the study.
- Systemically healthy patients.
Exclusion Criteria:
- The study excluded patients with a history of associated systemic disease.
- Cases of chronic aphthous stomatitis (major), lesions of herpetic form, numerous aphthae, and smoking.
- Patients with a history of hypersensitivity to the used agents.
- Pregnancy and lactation