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A Real-World Evidence Study of Goniotomy With the C-REX™ Instrument in Patients With Primary Open Angle Glaucoma

A Real-World Evidence Study of Goniotomy With the C-REX™ Instrument in Patients With Primary Open Angle Glaucoma

Recruiting
22 years and older
All
Phase N/A

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Overview

This study enrolls adults with primary open angle glaucoma (POAG) who underwent goniotomy intraocular pressure (IOP)-lowering surgery with the C-Rex Instrument. Patients are consented prior to surgery and followed for 12 months postoperatively. Data regarding IOP, use of glaucoma medications, and any device-related complications are collected during the study time period.

Description

This a multicenter, observational real-world evidence study of eligible adults with primary open angle glaucoma (POAG) in whom ab-interno goniotomy surgery with the C-Rex Instrument was performed.

Data is collected from the preoperative visit(s) that directly preceded the surgery, the surgical procedure, and post-surgical visits through 12 months postoperatively.

Specific data collected includes C-Rex Instrument goniotomy surgical details, preoperative and postoperative IOP and use of ocular hypotensive medications, and device-related safety events.

Eligibility

Inclusion Criteria:

  • Primary open angle glaucoma
  • Goniotomy surgery performed using the C-Rex Instrument

Exclusion Criteria:

  • History of intraocular surgery within 8 weeks prior to C-Rex surgery
  • Preoperative IOP higher than 33 mmHg
  • Presence of a glaucoma type other than POAG
  • Presence of clinically significant intraocular pathology other than cataract or glaucoma

Study details
    Primary Open Angle Glaucoma (POAG)

NCT06615661

Iantrek, Inc.

15 October 2025

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