Overview
The purpose of this study is to identify the effects of non-pharmacological and pharmacological anti-hypotensive treatment interventions on orthostatic hemodynamic responses, symptoms of autonomic dysreflexia and orthostatic hypotension, and levels of fatigue and comfort in hypotensive individuals with SCI.
Eligibility
Inclusion Criteria:
- traumatic spinal cord injury
- at least 12 months post injury
- injury level of C1-T6
- AIS A, B or C
- non-ambulatory
- non-ventilator
Exclusion Criteria:
- Active psychiatric disorder
- Stroke or cerebrovascular disease
- Alzheimer's Disease or dementia
- Unmanaged cardiac arrhythmias
- Concurrent systemic, hepatic, or renal disease
- Suspected or diagnosed malignancy
- Neurological disease other than SCI
- Self-reported history of three or more symptomatic episodes of AD per day