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Tranexamic Acid Use for Bleeding Prevention in the Surgical Treatment of Metastatic Spinal Tumor in Lung Cancer Patients

Tranexamic Acid Use for Bleeding Prevention in the Surgical Treatment of Metastatic Spinal Tumor in Lung Cancer Patients

Recruiting
10-80 years
All
Phase 1/2
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Overview

Massive blood loss occurs in metastatic spinal tumor resection and may cause severe complications. The objective of this study is to investigate whether the use of tranexamic acid will reduce perioperative and postoperative bleeding when compared to those without use of tranexamic acid.

Eligibility

Inclusion Criteria:

  • Diagnosed as metastatic carcinoma of the thoracolumbar spine
  • solitary neoplasm involve only one segment of spine
  • patients underwent separation surgery

Exclusion Criteria:

  • coagulation function was abnormal preoperatively
  • patients are allergic to tranexamic acid
  • neoplasm involve more than one segment of spine
  • patients with rich blood supply who need embolization

Study details
    Metastasis Spinal Tumor

NCT06023212

Second Affiliated Hospital, School of Medicine, Zhejiang University

15 October 2025

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