Overview
The investigators aimed to compare efficacy and safety of Propess versus Cooks double-balloon catheter for cervical ripening with an unfavorable cervix in term pregnancy.
Description
Previous studies focused on use of PGE2 instead of Propess, which is a preparation of PGE2 packaged in a hydrogel polymer matrix and release 10mg dinoprostone at 0.3mg per hour for 24 hours. Compared with PGE2, Propess can achieve a shorter induction-to-birth interval, a higher rate of vaginal delivery within 24 hours, and a smaller number of vaginal examinations during delivery. However local studies comparing the efficacy and satisfaction of cervical priming between Cook double-balloon catheter and Propess were lacking. The investigators aimed to compare efficacy and safety of Propess versus Cooks double-balloon catheter for cervical ripening with an unfavorable cervix in term pregnancy.
Eligibility
Inclusion Criteria:
- Viable singleton pregnancy
- Cephalic presentation
- Bishop score <7
- At term (>=37+0 weeks of gestation)
- Nulliparous women
Exclusion Criteria:
- Gestation <37weeks
- Multiple pregnancy
- Bishop score <7
- Malpresentation
- Contraindication to vaginal delivery
- Previous Caesarean section
- History of myomectomy
- Maternal fever
- Suspected infection
- Abnormal fetal heart-rate patterns
- Rupture of membranes
- Intrauterine growth restriction
- Not fit for giving consent
- Allergic to Propess or PGE2