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BOLSTER: Learning New Skills to Thrive

BOLSTER: Learning New Skills to Thrive

Recruiting
18 years and older
All
Phase N/A

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Overview

This research study is evaluating a new program called Building Out Lifelines for Safety, Trust, Empowerment, and Renewal or (BOLSTER), which was designed to support participants with a gynecological or gastrointestinal cancer and new and complex care needs.

Description

This multi-center, randomized trial is to test the efficacy of the BOLSTER Program and to improve participant quality of life (QOL), alleviate symptoms, reduce burden, and decrease the need for hospital care in participants with complex care needs from advanced gastrointestinal and gynecologic (GI/GYN) cancers.

The research study procedures include screening for eligibility, questionnaires, and telehealth visits.

Participation in this research study is expected to last about 12 weeks.

About 300 dyads (patients with family caregivers) are expected to participate in this research study.

The National Cancer Institute is funding this research study by providing funding.

Eligibility

Participant Inclusion Criteria:

  • Age ≥18 years
  • Currently hospitalized with skilled care need or have acquired a new skilled care need as an outpatient
  • Diagnosed with advanced gastrointestinal cancer (esophageal, gastric, pancreatic, hepatobiliary, colorectal, unknown GI primary, anal) or advanced gynecologic cancer (ovarian, endometrial, cervical, vaginal, vulvar)
  • Has a complex care need (e.g., ostomy, ileostomy, urostomy, nephrostomy, biliary drain, venting gastric tube, feeding tube, intraabdominal or pleural catheter, wound VAC)
  • Plans to receive ongoing cancer treatment
  • Has a family caregiver or friend (hereafter designated family caregiver) willing to participate
  • Able to speak and read English or Spanish (self-report)
  • Are willing to be audio-recorded
  • Have the cognitive/physical ability to participate in a 60-minute interview

Family or Caregiver Inclusion Criteria:

  • Age ≥ 18 years
  • Identified by a patient (as defined above) as a family or friend who is involved in their care.
  • Willing to participate in study visits
  • Willing to be audio recorded

Participant Exclusion Criteria:

  • Has cognitive impairments (as determined by the patient's oncologist)
  • Planning to enroll in hospice
  • Unable to complete baseline survey
  • Adults unable to consent
  • Individuals who are not yet adults (infants, children, teenagers)
  • Prisoners

Family or Caregiver Exclusion Criteria:

  • Unable to complete baseline survey
  • Adults unable to consent
  • Individuals who are not yet adults (infants, children, teenagers)
  • Prisoners

Study details
    Gastrointestinal Cancer
    Gynecologic Cancer
    Advanced Cancer

NCT06936878

Dana-Farber Cancer Institute

15 October 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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