Image

ES Catheter vs Cryoablation After Pectus Surgery

ES Catheter vs Cryoablation After Pectus Surgery

Recruiting
12-21 years
All
Phase N/A

Powered by AI

Overview

Participants will be randomized to receive ES catheter or cryoablation for pain management after the Nuss procedure. The goal of this study is to compare the following between the two groups:

  • Time to achieve short-term physical therapy goals and long-term functional outcomes
  • Compare immediate and long-term postoperative opioid use
  • Compare numbness on chest of postoperative day 1 and the return of sensation to baseline
  • Compare the incidence of neuropathic pain and other complications

Participants will receive surveys for up to 12 months postoperatively.

Eligibility

Inclusion Criteria:

  • Age 12 - 21 years
  • History of pectus excavatum
  • Scheduled for Nuss procedure

Exclusion Criteria:

  • Prior pectus repair
  • Other concomitant surgeries
  • Chronic pain conditions including Ehlers Danlos Syndrome
  • Non-English speaking - rationale: the questionnaires used in the study are in English language and the social and cultural factors of pain perception of non-English speaking patients could affect the study power
  • Severe developmental delays including cognitive (difficulties understanding), motor (cerebral palsy or muscular dystrophy), and speech delays (difficulties communicating)
  • History of or active renal or liver disease
  • Major surgery requiring opioids in the last 2 years
  • Severe respiratory problems (such as obstructive sleep apnea, cystic fibrosis, pulmonary fibrosis, or pneumonia within the last month)
  • Cardiac conditions including, but not limited to, cyanotic heart disease, hypoplastic left ventricle, arrhythmia, uncontrolled hypertension with ongoing treatment, Kawasaki disease, or cardiomyopathies. Participants with asymptomatic valvular lesions or defects may be included
  • BMI >35
  • Pregnant or breastfeeding females

Study details
    Pectus Excavatum

NCT06682208

Children's Hospital Medical Center, Cincinnati

15 October 2025

Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.