Overview

The purpose of the study is to compare soft tissue volume changes in terms of volume gain and stability around dental implants and PROMS in cases where a sub-epithelial connective tissue graft (SCTG) from the palate, Porcine collagen matrix (CM) or Porcine Acellular dermal matrix (PADM) is used after 3 and 15 months after implant placement.

Eligibility

Inclusion Criteria:

Patients referred to Department of Periodontology (CUO) in need of a single implant and need of soft tissue augmentation such as buccal defects, thin biotype, lack of keratinized tissue and aesthetic compromised situation.

• The patient must be ≥18 years and able to understand the nature of the proposed surgery and must sign an informed consent.
• The implant must be located between 2 fixed reference points (i.e. clinical crowns).
• Anterior and premolar teeth (from premolar to premolar).
• Enough crestal bone width to leave a minimum thickness of 2mm at the buccal bone plate when placing the implant.
• Palate must have ≥2mm of thickness at premolar area.
• Full mouth plaque and bleeding score <20%.

Exclusion Criteria:

• Pregnant or lactation.
• Active periodontal disease.
• Previous soft tissue augmentation in the area.
• Need of guided bone regeneration (GBR) during or after the placement of the implant.
• Heavy smokers (> 10 cigarettes per day).
• Local or systemic conditions that would interfere with routine periodontal therapy (non-controlled diabetes mellitus, cancer, HIV, Chronic High dose steroid therapy, bone metabolic diseases, radiation, immunosuppressive disorders, liver function disorder, immunosuppressant disease, autoimmune disease).
• Allergy to non-steroidal anti-inflammatory drugs.
• Patients taking medications that cause gingival enlargement.