Image

Evaluation of Wear Experience With a Weekly Replacement Soft Contact Lens in Neophyte Lens Wearers With Astigmatism

Evaluation of Wear Experience With a Weekly Replacement Soft Contact Lens in Neophyte Lens Wearers With Astigmatism

Recruiting
18-40 years
All
Phase N/A

Powered by AI

Overview

This open-label study is of adults with astigmatism who have never worn contact lenses. Subjects will be fit into a one week planned-replacement contact lenses and will wear lenses for approximately 3 weeks. Subjects will return for vision and lens fit assessments and will complete surveys about their wear experience.

Eligibility

Inclusion Criteria:

  1. Subjects must be new to contact lenses and have astigmatism of -0.75 or greater (within the parameters available for the P7fA lenses)
  2. Subjects must have 20/20 or better best corrected visual acuity.
  3. Good general health (defined by medication use that has not changed within the last month and the absence of medical conditions or treatments that are deemed confounding to the data as determined by the PI)
  4. Ability to give informed consent
  5. Willing to spend time for the study. Subjects will be required to attend three study visits and wear contact lenses on days between study visits.
  6. Willing and able to wear contact lenses for at least 8 hours per day for 5 days per week during the study as daily wear.
  7. Currently not using eye lubricating drops and willing to not use during study.
  8. Either gender and 18-40 years of age.
  9. Any racial or ethnic origin

Exclusion Criteria:

  1. Any active ocular inflammation or infection.
  2. Has a systemic condition that in the opinion of the investigator may affect a study outcome variable.
  3. Are presbyopic and require or habitually uses reading glasses for near work
  4. Is using any systemic or topical medications that in the opinion of the investigator may affect a study outcome variable
  5. History of refractive surgery
  6. Meets the diagnosis of dry eye disease with OSDI screening score ≥13.
  7. Known history of allergy or sensitivity to contact lens solutions and/or sodium fluorescein
  8. Is pregnant or lactating or planning a pregnancy during enrollment in the study
  9. Is participating in another clinical research study that includes invasive ocular tests
  10. An inability to perform contact lens application and removal after instruction.

Study details
    Astigmatism Bilateral

NCT06751225

Ohio State University

15 October 2025

Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.