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A Prospective, Multi-center, Real-world Study of Ovarian Metastatic Colorectal Cancer Patients

A Prospective, Multi-center, Real-world Study of Ovarian Metastatic Colorectal Cancer Patients

Recruiting
18 years and older
Female
Phase N/A

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Overview

This prospective, multi-center, real-world study is conducted to investigate the impact of different treatment strategies (systemic chemotherapy combined with oophorectomy or with other local treatment or chemotherapy alone) on the prognosis of ovarian metastatic colorectal cancer patients.

Description

This study prospectively collects data of patients diagnosed with ovarian metastatic colorectal cancer, meeting inclusion criteria and signing the informed consent. Patients' treatment strategies and survival outcome in the real world will be faithfully recorded.

Eligibility

Inclusion Criteria:

  1. Histologically confirmed colorectal adenocarcinoma;
  2. Histologically or radiologically diagnosed with ovarian metastasis, whether or not combined with metastases in other organs;
  3. Women ≥18 years of age;
  4. Eastern Cooperative Oncology Group performance status score ≤2;
  5. Available imaging data if the disease is measurable according to RECIST criteria version 1.1; patients are eligible if there is no measurable lesion.
  6. Complete medical records;
  7. Informed consent form signed.

Exclusion Criteria:

  1. Not ovarian metastatic colorectal cancer confirmed by radiology or histology;
  2. Drug abuse or other medical, psychological and social disorders that would interfere with cooperation with the requirements of the study;
  3. Other conditions that would influence patient compliance;
  4. Pregnant or breastfeeding female; male and female unwilling to take any contraceptive measures.

Study details
    Ovarian Metastasis
    Colorectal Cancer

NCT04716257

West China Hospital

21 October 2025

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FAQs

Learn more about clinical trials

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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