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Digital Health Intervention for Self-Management and Telemonitoring in Chimeric Antigen Receptor (CAR-T) Therapy

Digital Health Intervention for Self-Management and Telemonitoring in Chimeric Antigen Receptor (CAR-T) Therapy

Recruiting
18 years and older
All
Phase 3

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Overview

The overall purpose of this randomized control trial (RCT) is to determine the clinical effect of a multilevel, RPM-enhanced intervention during and after completion of outpatient CAR-T therapy in 190 patients and their family caregivers (FCGs).

Eligibility

Inclusion Criteria:

Patient Inclusion Criteria Informed Consent and Willingness to Participate

  1. Documented informed consent of the participant and/or legally authorized representative Age and Language Criteria
  2. Age ≥ 18 years old at the time of enrollment
  3. Ability to read and understand English or Spanish for Questionnaires Nature of Illness and Treatment Related Criteria
  4. Relapsed or refractory hematologic malignancy
  5. Scheduled to receive outpatient standard of care (SOC) CAR-T therapy
  6. Has a FCG committed to living with the patient for the duration of the study

Family Caregiver Inclusion Criteria Informed Consent and Willingness to Participate

  1. Documented informed consent of the participant and/or legally authorized representative Age and Language Criteria
  2. Age ≥ 18 years old at the time of enrollment
  3. Ability to read and understand English or Spanish for Questionnaires Nature of Illness and Treatment Related Criteria
  4. Family member or friend identified by the patient and defined as a person who knows the patient well and is involved in the patient's medical care

Exclusion Criteria 1. An employee who is under the direct/indirect supervision of the PI/ a co-investigator/ the study manager 2. A direct study team member

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Study details
    Hematologic Malignancies

NCT07186192

City of Hope Medical Center

1 November 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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