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Inflammation Markers in Fluid Aspirate From a Scarred Uterine vs. a Normal Uterine Cavity

Inflammation Markers in Fluid Aspirate From a Scarred Uterine vs. a Normal Uterine Cavity

Recruiting
18-40 years
Female
Phase N/A

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Overview

A prospective study that will take place in the hydrosonography clinic, comparing patients with an intact uterus to those who had a caesarean section. Eligible patients will preform a transvaginal ultrasound for evaluation of presence of a niche. After fixation of the transcervical catheter, we will flush 2 ml sterile NaCl 0.9% into the uterine cavity and aspirate the fluid. After collecting all samples, the samples will be snap frozen and stored at -80o C, until they undergo an immunological analysis.

Eligibility

Inclusion Criteria:

  • Patients suffering from infertility and assigned for a hydrosonography exam for assessment of the integrity of the uterus and fallopian tubes.

Exclusion Criteria:

  1. Patients with hydrosalpinx/pyosalpinx/sactosalpinx
  2. Patients who went through surgical correction of a niche
  3. Hormonal treatment- estrogens or progestins.
  4. Immunosuppressive/immunomodulating medication

Study details
    Infertility Due to Nonimplantation
    Infertility Secondary
    Cesarean Section Complications

NCT06322498

Hadassah Medical Organization

21 October 2025

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