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Analgesic Efficacy of Erector Spinae Plane Block vs External Oblique Intercostal Plane Block in Subcostal Cancer Surgeries

Analgesic Efficacy of Erector Spinae Plane Block vs External Oblique Intercostal Plane Block in Subcostal Cancer Surgeries

Recruiting
18-65 years
All
Phase N/A

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Overview

This study aims to evaluate the impact of ultrasound-guided erector spinae plane block compared to ultrasound-guided external oblique intercostal plane block regarding management of postoperative acute pain in patients undergoing above Umbilical surgical procedure.

Description

Subcostal incisions in cancer surgeries as in hepatectomy and nephrectomy are a cause of severe pain and can lead to significant respiratory impairment. Regional anesthesia of the trunk and abdominal wall is usually centered on epidural analgesia.

Erector spinae plane block (ESPB) is the deposition of local anesthetic (LA) in the interfascial plane at the paraspinal region. It provides effective visceral and somatic analgesia.

The recently described external oblique intercostal plane block (EOIPB) is a simple, effective, and convenient block, particularly in the context of morbid obesity, at which local anesthetic (LA) is deposited in the interfacial plane deep to external oblique muscle at the sixth intercostal space. It provides a blockade of the thoracoabdominal nerves at the level of T6 to T10.

Eligibility

Inclusion Criteria:

  • Age (18-65) Years.
  • Both sexes.
  • Body mass index (BMI): (20-40) kg/m2.
  • American Society of Anesthesiology (ASA) physical status II, III.
  • Type of surgery; unilateral subcostal incision in hepatectomy and nephrectomy.

Exclusion Criteria:

  • Patient refusal.
  • Subcostal incisions that are crossing the midline or midline incision.
  • Age <18 years or >65 years
  • BMI <20 kg/m2 and >40 kg/m2
  • Known sensitivity or contraindication to drugs used in the study
  • Contraindication to regional anesthesia e.g. local infection at the site of introduction, pre-existing peripheral neuropathies, and coagulopathy.
  • Pregnancy.
  • Physical status ASA IV
  • patients on chronic analgesic therapy (daily morphine ≥30 mg or equivalent dose of other opioids or tramadol or any medication for neuropathic pain)
  • patients with a history of drug abuse
  • patients with neuropsychiatric diseases; patients with a history of chronic pain syndromes that may enhance sensitivity to pain, for example, fibromyalgia
  • All patients who are going to have severe intra- or post-operative bleeding or will require postoperative mechanical ventilation are also excluded from the study.

Study details
    Analgesia
    Erector Spinae Plane Block
    External Oblique Intercostal Plane Block
    Subcostal Cancer Surgeries

NCT06519708

National Cancer Institute, Egypt

21 October 2025

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