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Global Multicenter Registry on Transcatheter TRIcuspid Valve RePLACEment

Global Multicenter Registry on Transcatheter TRIcuspid Valve RePLACEment

Recruiting
18 years and older
All
Phase N/A

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Overview

The field of transcatheter tricuspid valve replacement (TTVR) is rapidly emerging and data on this topic are scarce. Particularly, little is known about which patients are at greatest risk of procedural complications, such as the timing and onset of conduction disturbances necessitating permanent pacemaker implantation, and how such patients are managed. On this background, the TRIPLACE Registry - an investigator-initiated global multicenter registry - is aimed at better understanding the safety and efficacy of orthotopic TTVR.

Description

The primary aims of the registry will be:

  • To examine the safety, efficacy, and long-term outcomes of TTVR
  • To assess the incidence of procedural complications and their correlations with adverse clinical outcomes
  • To investigate the impact of different pre/post-procedural factors on peri-procedural complications and long-term outcomes after TTVR
  • To explore the characteristics of patients deemed eligible for TTVR.

Eligibility

Inclusion Criteria:

  • Patients undergoing Transcatheter Tricuspid Valve Replacement
  • Native Tricuspid Valve disease
  • Orthotopic Tricuspid Valve Implantation

Exclusion Criteria:

  • Age under 18 years

Study details
    Tricuspid Regurgitation

NCT06033274

Montefiore Medical Center

15 October 2025

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