Overview

The goal of this natural history study is to learn more about the biological and clinical aspects of amyotrophic lateral sclerosis (ALS). This study's findings will help with drug discovery, biomarker discovery, and outcome measure validation. Adults living with ALS, other motor neuron diseases (MND), a known mutation related to ALS and healthy volunteers contribute prospective and retrospective data to this study remotely. The study is sponsored and conducted by the ALS Therapy Development Institute.

Eligibility

Inclusion Criteria:

• 18 years of age or older
• Can communicate in written English
• Has a diagnosis of ALS/MND or is a known carrier of an ALS associated mutation

Exclusion Criteria:

• Significant cognitive impairment that would prevent individual completion and understanding of the informed consent process.