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Exploring the Predictive Value of Electroencephalography Features in Perioperative Neurocognitive Disorders Following Cardiovascular Surgery

Exploring the Predictive Value of Electroencephalography Features in Perioperative Neurocognitive Disorders Following Cardiovascular Surgery

Recruiting
60 years and older
All
Phase N/A

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Overview

To explore the predictive value of Electroencephalography features in Perioperative Neurocognitive Disorders in patients undergoing cardiovascular surgery under general anesthesia

Description

Data was acquired on the ward using a 10-20 system with a standard 32-channel EEG cap and an EEG instrument (BP Company, Gilching, Germany). Patients were tested using cognitive assessment scales before and after surgery.

Cognitive levels were assessed 1 day before surgery and 1 week after surgery (7±2 days) using the Montreal Cognitive Assessment (MoCA) . Patients were followed up one month (30±2 days) after surgery using the Telephone version of the Montreal Cognitive Assessment Scale (T-MoCA).

Preoperative and postoperative electroencephalography brain network-related indexes (such as cluster coefficient, small world index, etc.) in patients with PND will be included in the analysis.

Eligibility

Inclusion Criteria:

  1. Written informed consent
  2. undergoing coronary artery bypass surgery or valve replacement surgery under general anaesthesia
  3. ASA grade: II-IV
  4. older than 60 years
  5. Able to complete cognitive function tests

Exclusion criteria:

  1. history of severe neurological diseases and psychiatric diseases
  2. history of drug abuse
  3. severe hearing or vision impairment
  4. preoperative delirium
  5. serious adverse reactions such as cardiac arrest and cardiopulmonary resuscitation during surgery
  6. patients undergoing secondary surgery in a short period
  7. participation in concurrent clinical trials

Study details
    Cardiovascular Surgery
    Perioperative Neurocognitive Disorders

NCT06692309

Beijing Chao Yang Hospital

15 October 2025

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