Overview

The aim of this prospective randomized controlled double-blinded study is to compare the efficacy of dexmedetomidine, MgSO4 and lidocaine for cough suppression during general anesthetic emergence as regard number and severity.

Eligibility

Inclusion Criteria:

• Aged 21-60 years.
• Both genders.
• Body mass index < 30 kg/ m2
• American Society of Anesthesiology (ASA) physical status I-II.
• Mallampati score class I or II.
• Patients undergoing surgery under general anesthesia.

Exclusion Criteria:

• Known allergy to study drugs.
• History of psychiatric illness.
• Patients with major organ diseases.
• Pre-existing neurological deficits.
• Body mass index >30 kg/m2.
• Active airway infection or history of tracheal and laryngeal surgery.
• Lower esophageal sphincter incompetence (and reflux).
• Increased intracranial and intraocular pressure.
• Use of cough-inducing medications
• Pregnant, and lactating women.