Overview
The purpose of this clinical trial is to observe the use of low-dose muscle relaxants in bronchoscopy intervention surgeries, compared with no muscle relaxants, in terms of the satisfaction of tracheal tube insertion after anesthesia induction, the incidence of laryngospasm, the grading of intraoperative cough and movement, and the recovery of patients after surgery. The main questions it aims to answer are:
- How safe and feasible is the use of low-dose muscle relaxants in bronchoscopy intervention surgeries?
- Is the muscle relaxant regimen better than the no-muscle-relaxant regimen?
Participants will:
- During anesthesia induction, the experimental group will use low-dose muscle relaxants for anesthesia, while the control group will not use muscle relaxants for anesthesia.
- Record the satisfaction of mask ventilation and the incidence of laryngospasm.
Description
Patients scheduled for endoscopic interventional surgery were randomly divided into two groups: Group A (without muscle relaxation) and Group B (with muscle relaxation). Group A (intravenous administration of lidocaine 0.5mg/kg, remimazolam 0.2mg/kg, and remifentanil 3ug/kg); Group B (intravenous administration of lidocaine 0.5mg/kg, remimazolam 0.2mg/kg, remifentanil 3ug/kg, and rocuronium 0.15mg/kg). The total air flow rate was 6L/min, with oxygen-air ratio of 1:1. Both groups used standard techniques to insert the appropriate-sized laryngeal mask. The muscle rigidity grade after anesthesia induction, the satisfaction of laryngeal mask insertion, the incidence of laryngeal spasm, the grading of intraoperative cough, and the recovery of patients after surgery were recorded.
Eligibility
Inclusion Criteria:
- Patients undergoing elective electronic bronchoscopic interventional surgery;
- Age 18 years or older;
- American Society of Anesthesiologists (ASA) I-III;
- The duration of bronchoscopic surgery >=20min;
- Through pre-anesthesia assessment, the patient/family member has informed consent and signed the consent form;
- The general clinical information of the patient is complete.
Exclusion Criteria:
- Patients with predictable difficult airway;
- Small mouth opening (<2 transverse fingers);
- Combined with severe cardiovascular disease, abnormal liver and kidney function;
- Morbidly obese patients with body mass index (BMI) greater than 35kg/m^2;
- Has a history of gastroesophageal reflux disease.
- High risk of reflux aspiration;
- Those who have a history of abnormal surgical anesthesia recovery in the past;
- Patients with mental illness and previous allergies to conventional anesthetic drugs.