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Association Between Blood Pressure and Risk of PSCI

Association Between Blood Pressure and Risk of PSCI

Recruiting
18-90 years
All
Phase N/A

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Overview

This retrospective cohort study was designed to explore the relationship between blood pressure and cognitive impairment after stroke

Description

Patients who have been followed up for more than 3 months after stroke will be included in the study. Basic data of patients and factors that may be related to cognitive impairment will be collected, and the relationship between blood pressure and cognitive impairment after stroke will be explored by univariate regression analysis and multivariate regression analysis. Univariate logistic regression model and multivariate logistic regression model were used to explore the relationship between blood pressure level and the risk of cognitive impairment after stroke, and the effect of blood pressure level and cognitive impairment sub-line in different patients was evaluated by subgroup analysis.

Eligibility

Inclusion criteria:

  1. Patient diagnosed with stroke by CT or MRI,
  2. Patients completed the MMSE scale at least once during hospitalization
  3. The follow-up time was more than three months after the stroke occurred;

Exclusion criteria:

  1. Patients with incomplete data, follow-up time less than three months after the stroke occurred less than 3 months,
  2. Patients with pre-existing cognitive impairment before stroke according to their medical records,
  3. patients failed to complete MMSE assessment because of aphasia or any other reasons,
  4. Patients combined with malignant tumors, patients combined with psychiatric disorders.

Study details
    Stroke
    Cognitive Decline
    Blood Pressure

NCT06730711

First Affiliated Hospital of Chongqing Medical University

21 October 2025

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