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AI Assisted Personalized Legacy Program (Reflections: My Story) for Patients With Serious Illness

AI Assisted Personalized Legacy Program (Reflections: My Story) for Patients With Serious Illness

Recruiting
18 years and older
All
Phase N/A

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Overview

The purpose of this study is to determine if it is feasible and acceptable to recruit for and deliver the AI Assisted Personalized Legacy Program intervention to patients with serious illness.

Description

This study is an investigator-initiated, multi-site Mayo Clinic prospective minimal risk pilot study to determine feasibility and acceptability of an AI Assisted Personalized Legacy Program. The AI Assisted Personalized Legacy Program intervention is a brief, individualized psychotherapy that aims to relieve psycho-emotional and existential distress and improve the experiences of patients whose lives are impacted by serious illness. This therapy offers patients an opportunity to reflect on their life with a trained facilitator and share their thoughts and memories with family and other people in their life. The sessions are recorded and transcribed. The interventionist will work with patients to edit the document and provide a final legacy document for patient to keep and give to loved ones.

Eligibility

Participant population: Adults with serious illness - defined as a health condition that carries a high risk of mortality

Inclusion Criteria for patients:

  1. Age ≥18 years
  2. English fluency
  3. Provide informed consent
  4. Ability to complete questionnaire(s) by themselves or with assistance

Exclusion Criteria:

  1. Other psychological co-morbidities such as untreated schizophrenia, bipolar disease
  2. Recent suicide attempt or psychiatric illness severe enough that hospitalization has been necessary in last 6 months
  3. Active delirium
  4. Advanced dementia
  5. Participation in concurrent legacy offerings through the palliative care clinic

Study details
    Serious Illness
    Existential Distress

NCT07009210

Mayo Clinic

15 October 2025

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