Image

Ecological Momentary Intervention for Reward in Anhedonia

Ecological Momentary Intervention for Reward in Anhedonia

Recruiting
18 years and older
All
Phase N/A

Powered by AI

Overview

The present study evaluates a two week ecological momentary intervention (EMI) in reducing anhedonia and psychological distress (i.e. elevated depression, stress and anxiety). Participants in the experimental group complete three daily exercises targeting reward-related processes, including positive mental imagery, savoring, gratitude, taking ownership for positive experience, and silver lining. These components were selected to improve reward anticipation as well as reward consumption and reward learning as the underlying mechanisms of anhedonia. An active control group receives progressive muscle relaxation training, matched in format and frequency. Exercise units are presented using audio recordings via smartphone app.

Description

Anhedonia, the diminished ability to experience positive emotions such as pleasure, is a clinically relevant condition central to depression and frequently observed across a range of other psychological disorders including anxiety disorders or chronic stress. Despite its prevalence and impact on quality of life, effective interventions specifically targeting anhedonia remain limited. Standard cognitive-behavioral therapies (CBT) often reduce negative affect (e.g., sadness, anxiety) but tend to be less effective in enhancing positive affect. Moreover, anhedonia has been proposed as a potential limiting factor in the efficacy of exposure-based treatments for anxiety disorders, underscoring the need for low-threshold interventions that directly target reward-related deficits.

At the core of anhedonia lies impaired reward processing, which involves multiple phases: (1) reward anticipation (wanting), (2) reward consumption (liking), and (3) reward-based learning. Individuals with elevated anhedonia often show deficits across these domains, leading to reduced engagement in rewarding activities and motivational impairments. Therefore, effective interventions should aim to strengthen these specific facets of reward functioning.

Emerging approaches such as Positive Affect Treatment (PAT) have demonstrated promising effects by combining components like positive mental imagery, savoring, self-reinforcement (i.e., taking ownership of positive experiences), and cognitive reframing (e.g., silver lining techniques). Complementary evidence suggests that gratitude-based interventions can enhance well-being and buffer against stress, based on the idea that gratitude and negative affect are partially incompatible.

Building on these findings, the current study tests a two-week ecological momentary intervention (EMI) designed to enhance reward processing and reduce anhedonia in daily life. The intervention is delivered via the smartphone app m-Path and comprises three brief training units per day. These include a combination of audio-guided exercises and ecological momentary assessments (EMA) capturing mood, activity, and psychological symptoms. The exercises target positive mental imagery, savoring, gratitude, silver lining, and taking ownership of positive experiences-each mapped onto distinct components of reward processing. EMI formats offer the advantage of flexibility and integration into everyday contexts without requiring direct clinician contact.

Participants are randomly assigned to either the reward-focused intervention group or an active control group. The control group receives a structurally equivalent two-week training consisting of progressive muscle relaxation (PMR) exercises, also delivered via the m-Path app. PMR is an established stress-reduction technique and serves as an active comparator matched in format, frequency, and duration. The control group completes two audio-guided PMR sessions per day and one brief reflection unit each evening.

It is hypothesized that the reward intervention will (a) reduce anhedonia and psychological distress more effectively than PMR and (b) lead to specific improvements in reward processing.

Eligibility

Inclusion Criteria:

  • German speaking
  • Smartphone available and willingness to participate in repeated training units and questions delivered via app
  • Clinically elevated anhedonia (SHAPS >= 25) and elevated depression (DASS-21-Depression >= 10), elevated anxiey (DASS-21-Anxiety >= 6) or elevated stress (DASS-21-Stress >= 10)

Exclusion Criteria:

  • Psychotropic medication
  • Psychotherapy currently ongoing or planned during participation
  • Suicidality, lifetime diagnosis of bipolar disorders or psychotic episodes

Study details
    Anhedonia
    Anxiety
    Stress
    Depression

NCT07155941

Philipps University Marburg

15 October 2025

Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.