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App-Based Optimization of Long-Term CPAP Adherence and Quality of Life

App-Based Optimization of Long-Term CPAP Adherence and Quality of Life

Recruiting
18 years and older
All
Phase N/A

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Overview

The purpose of this study is to optimize the time of CPAP usage to at least 6 hours a night for 6 nights per week for people who have OSA with the help of a smartphone application called SmartWell24. This application aims to target CPAP adherence.

Eligibility

Inclusion Criteria:

  • In both trials of Aim 2, twenty adults (≥18 years) per trial will be recruited who are newly diagnosed with OSA and speak English.
  • In both trials, we will purposely recruit samples balanced by biological sex and OSA severity (apnea hypopnea index: 5-14 vs. ≥ 15).
  • Inclusion Criteria are the same for both Aim 2 trials; Adult patients from MCCSM sites who:
    • Are diagnosed with OSA based on clinical diagnostic testing via laboratory or home-based sleep study;
    • Own and have the functional and cognitive ability to use an Apple (iOS9 or higher) or Android (4.2 or higher) smartphone with minimal to no assistance;
    • Are prescribed continuous or auto-titrated CPAP;
    • Agree to using a smartphone application and wearable wrist sensor; and
    • Speak and read English.

Exclusion Criteria:

  • Unwilling to complete study measures and engage with SleepWell24;
  • Refuse to not use the Fitbit application during the study trial;
  • Have any conditions that would impede full participation (e.g., communication or cognitive impairments that limit ability to read and/or follow directions, other acute or severe health, cognitive, or psychological conditions);
  • Currently participating in other lifestyle programs (e.g. active, formal weight loss program or research study; smoking cessation program, etc.);
  • Decide to use a different PAP device than ResMed Airsense 10;
  • Prescribed high-dose benzodiazepines (equivalent to > 1 mg lorazapam/night);
  • Daily opioid medication use at night;'
  • Unwilling to discontinue use of any current wearable sensor for the duration of the trial;
  • Previous documented history of treatment/referral for claustrophobia;
  • Previous CPAP use;
  • Currently engaging in shiftwork defined as night shift or rotating day and night shifts; and
  • Currently pregnant, trying to conceive, or breastfeeding.

Study details
    Obstructive Sleep Apnea

NCT06381115

Mayo Clinic

15 October 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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