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Ginger to Prevent Nausea and Vomiting After Laparoscopic Cholecystectomy

Ginger to Prevent Nausea and Vomiting After Laparoscopic Cholecystectomy

Recruiting
18 years and older
All
Phase 4

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Overview

This study aims to evaluate whether preoperative oral administration of ginger (800 mg, given 2 hours before surgery) reduces the incidence and severity of postoperative nausea and vomiting (PONV) within the first 24 hours after laparoscopic cholecystectomy.

Eligibility

Inclusion Criteria:

  • Age ≥ 18 years.
  • Scheduled for elective laparoscopic cholecystectomy under general anesthesia.
  • American Society of Anesthesiologists (ASA) physical status I-III.
  • Able to understand the study procedures and provide written informed consent.

Exclusion Criteria:

  • Known allergy or hypersensitivity to ginger
  • Documented history of bleeding disorders or current treatment with anticoagulant agents
  • History of severe postoperative nausea and vomiting or an Apfel score of 4
  • Administration of antiemetic drugs or corticosteroids during the preoperative period
  • Pregnancy or breastfeeding
  • Active gastrointestinal or liver disease

Study details
    Postoperative Nausea and Vomiting
    Laparoscopic Cholecystectomy

NCT07190495

University Tunis El Manar

15 October 2025

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