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Immune Biomarkers in Prostate Cancer Patients Treated With Brachytherapy

Immune Biomarkers in Prostate Cancer Patients Treated With Brachytherapy

Recruiting
18 years and older
Male
Phase N/A

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Overview

Analysis of peripheral immune cells before, during, and after brachytherapy treatment. Corresponding analysis of tissue samples collected during brachytherapy treatment.

Eligibility

Inclusion Criteria Arm 1:

  • Primary treatment with I-125 seeds or HDR-BT
  • No previous treatment for prostate cancer
  • Age ≥ 18 years

Inclusion Criteria Arm 2:

  • HDR- or PDR-BT
  • No radiation therapy within three months before salvage treatment
  • Complete documentation available on previous treatment for prostate cancer
  • No history of prostatectomy
  • Age ≥ 18 years

Exclusion Criteria:

  • Pre-existent auto-immune disease
  • patients under bloodthinning medication
  • substance abuse

Study details
    Prostate Cancer (Diagnosis)
    Prostate Cancer Patients Who Have Brachytherapy Seed Implant
    Prostate Cancer Patients Treated by Radiotherapy
    Prostate Cancer Recurrent

NCT07131956

University of Erlangen-Nürnberg Medical School

15 October 2025

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