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A Study of Genetic Influence on LDL Hyper-responsiveness in Patients Following a Ketogenic Diet

A Study of Genetic Influence on LDL Hyper-responsiveness in Patients Following a Ketogenic Diet

Recruiting
18 years and older
All
Phase N/A
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Overview

The purpose of this study is to identify whether individuals following a ketogenic diet who experience extreme LDL-C elevation, termed "hyper-responders", have identifiable genetic variations in genes involved in cholesterol absorption.

Eligibility

Inclusion Criteria:

  • 18 years of age or older
  • LDL-C >170 mg/dL in response to starting a ketogenic diet

Exclusion Criteria:

  • Patients who do not consent to blood draw for genetic testing
  • Those with LDL-C <170 mg/dL on a ketogenic diet

Study details
    LDL Hyper-responsiveness

NCT07137286

Mayo Clinic

15 October 2025

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