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Effectiveness of Intraseptal Anesthesia for Periodontal Surgical Procedures

Effectiveness of Intraseptal Anesthesia for Periodontal Surgical Procedures

Recruiting
18 years and older
All
Phase N/A

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Overview

The primary aim of this study is to evaluate the efficacy of intraseptal anesthesia using 0.3 mL of 4% articaine with 1:100,000 epinephrine (4% Ar+Ep) in periodontal flap surgery for periodontitis and in gingivectomy/gingivoplasty for the excision of hyperplastic gingival enlargements. The secondary aim is to compare clinical anesthetic parameters between ISA and conventional anesthesia techniques.

Description

In test groups every patient is going to receive injections of 0.3 mL of 4% articaine with 1: 100,000 epinephrine (ORABLOC ® , 40 mg/ml Articaine + 0.01 mg/ml Epinephrine, PIERREL S.P.A, Capua, Italy), with a computer controlled anesthesia delivery sistem (Anaeject®, Septodont, Sallanches, France). In the control groups all surgical procedures is going to be performed under infiltration anesthesia, as commonly used in periodontal surgery. The success rate and the anesthetic field widths were recorded by pinprick testing. Pain levels were recorded using a visual analogue scale (VAS) for the administration of anesthesia, during the surgical procedure and after the intervention.

Eligibility

Inclusion Criteria:

  • age ≥18 years good systemic health
  • gingivitis or periodontitis stage II and III
  • at least 20 teeth present.

Exclusion Criteria:

  • allergy to 4%Ar+Ep
  • pregnant or lactating females
  • medication uptake and diseases affecting the periodontal tissues
  • acute pain, swelling, and presence of gingival lesions.

Study details
    Periodontitis
    Gingivitis and Periodontal Diseases

NCT07212270

University of Belgrade

15 October 2025

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