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Frailty Among Renal Transplant Recipients and Relation to Chronic Allograft Dysfunction

Frailty Among Renal Transplant Recipients and Relation to Chronic Allograft Dysfunction

Recruiting
18 years and older
All
Phase N/A

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Overview

The aim of the study is to assess prevalence of frailty among renal transplant recipients in Alexandria University Hospitals and to study the relation between frailty and chronic allograft dysfunction.

Description

With respect to correlates of frailty, although higher comorbidity burden is also a risk factor for frailty among KT candidates, frailty can also occur in the setting of lower comorbidity burdens. Diabetes and serum albumin concentration are also associated with frailty among prevalent dialysis patients.

In addition, individuals with CKD and ESKD who are frail are also more likely to have cognitive impairment and sarcopenia, or low muscle mass, than their non-frail counterparts

Eligibility

Inclusion Criteria:

  • Renal transplanted patients with GFR more than 30

Exclusion Criteria:

  • Mentally or physically unfit patients.
  • Amputation of lower limb.
  • Active neoplasia, chronic liver disease, previous immunological disease.
  • Psychiatric disorders.
  • Pregnancy.

Study details
    Frailty
    Renal Transplant

NCT07181096

Alexandria University

15 October 2025

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