Overview

This randomized, double-blind clinical trial aims to evaluate the effectiveness of two medications-hydrocortisone ointment and lidocaine solution-applied to the endotracheal tube in reducing postoperative throat pain, hoarseness, and cough following thyroid or parathyroid surgery with neuromonitoring.

A total of 764 adult patients undergoing elective neck surgery at Saint-Petersburg State University Hospital will be enrolled and randomly assigned to receive either a hydrocortisone-coated or lidocaine-coated endotracheal tube.

Outcomes will be assessed upon awakening from anesthesia, at 24 hours, and again at 3 days postoperatively.

The findings may contribute to improving postoperative comfort and recovery for patients undergoing similar surgical procedures.

Eligibility

Inclusion Criteria:

• Patients scheduled for elective open surgery on the thyroid/parathyroid glands with intraoperative neuromonitoring.
• Age ≥18 years.
• Willing and able to provide voluntary informed consent for participation in the study.

Exclusion Criteria:

• Pregnancy (for women of childbearing potential).
• Known allergy to hydrocortisone or lidocaine.
• Refusal to participate in the study.