Image

Hearing Preservation in Cochlear Implantation Surgery

Hearing Preservation in Cochlear Implantation Surgery

Recruiting
18 years and older
All
Phase N/A

Powered by AI

Overview

In order to preserve the residual hearing in patients with sensorineural hearing loss (SNHL) receiving a cochlear implant (CI), the insertion trauma to the delicate and microscopic structures of the cochlea needs to be minimized. The surgical procedure starts with the conventional mastoidectomy-posterior tympanotomy (MPT) approach to the middle ear, and is followed by accessing the cochlea, with either a cochleostomy (CO) or via the round window (RW). Both techniques have their benefits and disadvantages. Another aspect is the design of the electrode array. There are fundamentally two different designs: a straight lateral wall lying electrode array (LW), or a pre-curved perimodiolar cochlear lying electrode array (PM). Interestingly, until now, the best surgical approach and type of implant is unknown. Our hypothesis is that the combination of a RW approach and a LW lying electrode array minimizes insertion trauma, leading to better hearing outcome for SNHL patients.

Eligibility

Inclusion Criteria:

  • Severe hearing loss, CI candidate
  • 18 years of age or older
  • normal function of middle ear (i.e. no acute middle ear infections)
  • dutch language proficiency
  • choice for Advanced Bionics implant

Exclusion Criteria:

  • prior otologic surgery in the implanted ear (excluding tympanostomy tube placement)
  • inner ear malformation present in the ear to be implanted (i.e. ossification, Mondini malformation)
  • retrocochlear pathology present in the auditory system to be implanted
  • neurocognitive disorders
  • sudden deafness

Study details
    Sensorineural Hearing Loss

NCT07146841

UMC Utrecht

15 October 2025

Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.