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Inflammatory Biomarkers as Predictors of PONV Following Pediatric Orchiopexy

Inflammatory Biomarkers as Predictors of PONV Following Pediatric Orchiopexy

Recruiting
1-8 years
All
Phase N/A
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Overview

Orchiopexy is a common surgical procedure for the treatment of cryptorchidism in the pediatric population, with a high incidence of postoperative nausea and vomiting (PONV).

Recent evidence suggests that systemic inflammation may contribute to PONV pathogenesis, and preoperative inflammatory biomarkers such as NLR, PLR, SII, MLR, and SIRI could serve as predictive indicators.

This prospective observational study aims to evaluate the relationship between these biomarkers and PONV incidence in children undergoing orchiopexy.

Eligibility

Inclusion Criteria:

  • Patients aged between 1 and 8 years
  • Patients with ASA physical status I-II
  • Patients scheduled for elective orchiopexy
  • Obtained written informed consent from parents/guardians

Exclusion Criteria:

  • Patients younger than 1 year or older than 8 years
  • Patients with ASA physical status III or higher
  • Presence of acute infection signs
  • History of previous nausea or vomiting

Study details
    Pediatric Anesthesia
    Postoperative Nausea and Vomiting (PONV)
    Inflammatory Biomarkers

NCT07148063

Diskapi Yildirim Beyazit Education and Research Hospital

15 October 2025

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