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Effect of High-intensity Interval Training Combined With DASH Diet on Arterial Stiffness in Hypertensive Patients

Effect of High-intensity Interval Training Combined With DASH Diet on Arterial Stiffness in Hypertensive Patients

Recruiting
35-50 years
All
Phase N/A

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Overview

Cardiovascular disease (CVD) is one of the leading causes of mortality worldwide and a major risk factor for morbidity worldwide . It is necessary to reduce the incidence and risk factors of CVD, as physical activity is known to reduce mortality from CVD. Arterial stiffness and hypertension are closely related in pathophysiology. Chronic high blood pressure (BP) can lead to arterial wall damage by mechanical stress, endothelial dysfunction, increased inflammation, oxidative stress, and renin-angiotensin-aldosterone system (RAAS) activation. HIIT has been shown to be equally or even better at stimulating health benefits than moderate-intensity continuous training (MICT) and is considered a time-saving aerobic exercise for reducing arterial stiffness in HTN patients

Eligibility

Inclusion Criteria:

  • Their age< 35 up to 50 years old
  • Both sexes.
  • Controlled HTN ( stage 1,B.P 140-159 mmhg / 90-99 mmhg and stage 2, B.P 160-179 mmhg-100-109 mmhg )
  • Hemodynamic stable. Able to provide informed consent

Exclusion Criteria:

  • Uncontrolled hypertension.
  • Severe HTN <180/110 mmhg
  • Renal dysfunction
  • Unstable cardiac conditions
  • Severe pulmonary disease that limit exercise
  • Impaired cognition
  • Musculoskeletal problems that made it difficult to do exercise

Study details
    Hypertension
    Arterial Stiffness

NCT07188272

Deraya University

15 October 2025

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