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Protein Supplementation and Resistance Training to Prevent Fat-Free Mass Loss Following Metabolic-Bariatric Surgery

Protein Supplementation and Resistance Training to Prevent Fat-Free Mass Loss Following Metabolic-Bariatric Surgery

Recruiting
18 years and older
All
Phase N/A

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Overview

The goal of this clinical trial is to investigate the effects of daily protein supplementation and participation in a weekly supervised resistance training program on the prevention of excessive muscle mass loss following bariatric surgery. Patients treated at one of the participating centers will be invited to participate and will be randomly assigned to one of two groups.

Participants in group 1 will receive standard postoperative care as currently provided. Participants in group 2 will also receive standard care, but in addition, they will be asked to consume extra protein daily and take part in a supervised resistance training session once a week.

Previous research has shown that approximately one in five patients undergoing bariatric surgery experiences excessive muscle loss after the surgery. It is known that resistance training and protein intake can help maintain and even improve muscle mass. However, limited research has been conducted on the combined effects of protein supplementation and resistance training in patients after bariatric surgery. Therefore, the aim of this trial is to determine whether participants receiving the additional intervention experience less muscle mass loss compared to those receiving standard care alone.

Eligibility

Inclusion Criteria:

  • A scheduled metabolic-bariatric surgery (i.e. RYGB or Sleeve Gastrectomy)
  • Participation in the NOK care program
  • Able to understand and perform the study procedures

Exclusion Criteria:

  • Allergic or sensitive for milk proteins, or lactose intolerant
  • Diagnosed renal insufficiency
  • Diagnosed intestinal diseases influencing the uptake of protein (i.e. active inflammatory bowel disease

Study details
    Bariatric Surgery
    Fat Free Mass

NCT07156552

Radboud University Medical Center

15 October 2025

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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