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Short-term Study of Two Soft Contact Lenses in Wearers With Low Astigmatism

Short-term Study of Two Soft Contact Lenses in Wearers With Low Astigmatism

Recruiting
17-42 years
All
Phase N/A

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Overview

The primary objective of the study is to evaluate and compare the performance of two soft contact lens.

Description

The primary objective of the study is to evaluate and compare the performance of two different soft contact lens in existing spherical soft contact lens (CL) wearers with low levels of refractive astigmatism over a 2-week wear period.

Eligibility

Inclusion Criteria:

  1. At least 17 years and no more than 42 years of age.
  2. Have read and signed the study consent form.
  3. Are willing and able to follow instructions and maintain the appointment schedule.
  4. Are habitual wearer of spherical soft contact lenses (not toric or multifocal design), any brand and any replacement frequency.
  5. Are willing to wear the study contact lenses for 6 days a week while in this study and on three days (day 1, Day 7 and Day 13) for at least 12 hours.
  6. Are willing to provide a contact email and telephone number and to use a device that allows them to respond to a short online questionnaire every 3 hours on days 1, 7 and 13 of each lens arm, while wearing one of the 2 study lenses.
  7. Are non-presbyopic i.e. no requirement for a reading addition for routine daily tasks (self report).
  8. Have astigmatism of either -0.50, -0.75, -1.00 or -1.25 DC in each eye by subjective sphero-cylindrical refraction.
  9. Achieves at least 0.10 LogMAR in each eye by subjective sphero-cylindrical refraction.
  10. Can be fit with available study contact lens powers of between +6.00 to -10.00 DS.
  11. Demonstrate an acceptable fit with the study contact lenses.

Exclusion Criteria:

  1. Are participating in any concurrent clinical interventional study.
  2. Have worn rigid contact lenses in the last 3 months.
  3. Have worn soft toric contact lenses in the past 3 months.
  4. Have any known active ocular disease or allergies and/or infection.
  5. Have clinically significant biomicroscopy findings or have an ocular condition that contraindicate contact lens wear.
  6. Have a systemic condition that in the opinion of the investigator may affect a study outcome variable or contraindicate wearing soft contact lenses.
  7. Are using any systemic or topical medications that in the opinion of the investigator may affect a study outcome variable or contraindicate wearing soft contact lenses.
  8. Have known sensitivity to the diagnostic sodium fluorescein to be used in the study.
  9. Have undergone refractive error surgery or intraocular surgery.
  10. Are an employee of the Centre for Ocular Research & Education directly involved in this study.

Study details
    Astigmatism
    Myopia
    Hyperopia

NCT06873048

CooperVision International Limited (CVIL)

14 October 2025

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