Overview
The goal of this observational study is to improve the early detection of lung cancer in adults who have smoked less than 100 tobacco cigarettes ("never-smokers") in the United Kingdom. The main questions it aims to answer are:
- To describe characteristics such as demographics, co-morbidities and environmental exposures
- To describe participant pathways including presentation mode and symptoms to understand if earlier diagnosis would be possible
- To describe participant outcomes such as cancer stage, treatment and mortality
- To quantitatively or qualitatively measure modifiable and non-modifiable factors that may be associated with LCINS including environmental measures, blood tests and genomic data.
Participants will currently have no change to their usual care.
Eligibility
Inclusion Criteria:
- All adult participants from age of 18 who are diagnosed or treated with primary lung cancer through radiology or histology at any participating study site
Exclusion Criteria:
- Participants who have ever smoked cigarettes or tobacco will be excluded; this is
defined as:
- More than 100 cigarettes or 75g tobacco in their lifetime
- Those who have received a prescription for nicotine replacement therapy
- For prospective participants, those who cannot consent will be excluded