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Modulation of Anti-tumor T Cell Responses in Cancer Patients Treated by Concomitant Radiochemotherapy

Modulation of Anti-tumor T Cell Responses in Cancer Patients Treated by Concomitant Radiochemotherapy

Recruiting
18 years and older
All
Phase N/A
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Overview

The aim of this study is to evaluate modulation of anti-tumor T cell responses in cancer patients treated by concomitant radiochemotherapy (i-RTCT)

Eligibility

Inclusion Criteria:

  • Histologically confirmed NSCLC (Non Small Cell Lung Cancer) or SCLC (small cell lung cancer) OR histologically confirmed Head and neck cancer
  • Patient candidate to a first-line concomitant radiochemotherapy
  • Written informed consent

Exclusion Criteria:

  • Sequential radiochemotherapy, exclusive radiotherapy, or stereotactic radiotherapy
  • History of adjuvant radiochemotherapy for cancer treatment
  • Patients under immunotherapy, chemotherapy or other immunosuppressive drugs (prednisone or prednisolone ≤ 10 mg/day is allowed)
  • HIV, hepatitis C or B virus
  • Patients with any medical or psychiatric condition or disease,
  • Patients under guardianship, curatorship or under the protection of justice.

Study details
    Lung Cancer
    Head and Neck Cancer

NCT03117946

Centre Hospitalier Universitaire de Besancon

17 September 2025

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