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UFPTI 2403-PR12: Real-Time Volumetric Ionizing Radiation Acoustic Imaging for In-vivo Proton Treatment Monitoring in Pencil-Beam Scanning

UFPTI 2403-PR12: Real-Time Volumetric Ionizing Radiation Acoustic Imaging for In-vivo Proton Treatment Monitoring in Pencil-Beam Scanning

Recruiting
18 years and older
Male
Phase N/A

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Overview

The purpose of this study is to evaluate the use of ionizing-radiation photo acoustic imaging (iRAI) for proton radiation treatment.

Eligibility

Inclusion Criteria:

  • Disease: Prostate cancer
  • Treatment site:
  • Prostate or prostate and seminal vesicle
  • No regional lymph node is involved
  • Patient's body weight: Patient's body weight is less than 350 lbs to consider the total weight limit that the ProteusONE treatment table and the robotic arm can operate
  • Treatment volume size: maximum size less than 15 x 15 cm in a cross-section and a thickness less than 20 cm to consider 2D transducer matrix size
  • Provision to sign the consent form and understand the non-invasiveness of iRAI
  • Patient agreement on tolerance on placing a water bag to acquire iRAI during treatment
  • Treatment modality: Proton radiation therapy with UFHPTI's ProteusONE gantry using PBS

Exclusion Criteria:

  • A patient who would not be tolerable or will feel nervous about being touched on the skin with a water bag
  • A patient with a significant medical implant or hardware in the treatment area

Study details
    Prostate Cancer

NCT06465966

University of Florida

16 September 2025

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