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Individualizing Corticosteroid Use in Pneumonia

Individualizing Corticosteroid Use in Pneumonia

Recruiting
18 years and older
All
Phase 2

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Overview

In this study, researchers propose a unique (individualized) approach to steroid treatment seeking to give the right dose of steroid to the right patient and at the right time. This study seeks to compare usual care to an individualized steroid dosing strategy by testing a marker of inflammation in the blood called C- reactive protein (CRP). The overall goal is to reduce an individual's exposure to steroids and the risk of potential side effects thereby increasing the potential benefit of using steroids to control inflammation in pneumonia.

Eligibility

Inclusion Criteria:

  • Hospitalized adult (≥ 18 years) patients.
  • Community acquired pneumonia.

Exclusion Criteria:

  • Contraindications or unwillingness to use corticosteroids by patient or provider.
  • History of adrenal insufficiency, septic shock, or another absolute indication for steroid use.
  • Suspected pulmonary vasculitis or other autoimmune pulmonary disorder.
  • Positive pregnancy test
  • Comfort care.

Study details
    Pneumonia

NCT05334316

Mayo Clinic

16 September 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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