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Phenotype and Multi-omics Analysis of Children With Congenital Diarrhea and Enteropathy in China

Phenotype and Multi-omics Analysis of Children With Congenital Diarrhea and Enteropathy in China

Recruiting
1-3 years
All
Phase N/A
  • Technical (Original)
  • Simplified (AI rewritten)

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Overview

This study will establish a clinical cohort of children with congenital diarrhea and enteropathy (CODE), mine biomarkers of CODE through multi-omics technology and construct a clinical risk prediction model.

Description

This study will establish a clinical cohort and a clinical phenotype database of children with congenital diarrhea and enteropathy (CODE), The investigator will mine biomarkers of CODE through multi-omics technology. This study is designed to construct a clinical risk prediction model by combining artificial intelligence technology.

Eligibility

Inclusion Criteria:

  • Patients with chronic diarrhea lasting greater than 2 months or greater than 1 month in patients younger than 2 months of age
  • Patients with consent from parents or legal guardians

Exclusion Criteria:

  • Chronic diarrhea caused by specific infections, i.e. CMV, Clostridioides difficile
  • Chronic diarrhea with necrotizing enterocolitis, short bowel syndrome
  • Functional diarrhea
  • Patients with poor compliance

Study details
    Diarrhea Infantile

NCT06356545

Children's Hospital of Fudan University

14 September 2025

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