Overview

This study aimed to assess the effectiveness of Coenzyme Q10 in preventing both acute and chronic pain following thoracoscopic surgery, with a focus on its potential benefits in reducing the incidence and severity of pain.

Eligibility

Inclusion Criteria:

• Aged 18-75 years;
• American Society of Anesthesiology (ASA) physical status classification I-III;
• Scheduled for elective lung resection surgery under thoracoscopy;
• Voluntarily opting for patient-controlled intravenous analgesia;
• Willing to participate in this trial after consultation with the patient or their family and signing the informed consent form.

Exclusion Criteria:

• History of previous thoracotomy or thoracoscopic surgery;
• Patients converted to open thoracotomy intraoperatively;
• Severe hepatic or renal dysfunction;
• History of substance abuse;
• Pregnancy or breastfeeding;
• History of chronic pain;
• Use of coenzyme Q10 for more than one month;
• Allergy to coenzyme Q10;
• Patients unable to communicate or cooperate.