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Does Intralipid Infusion Can Reverse the Spinal Anesthesia Effect in Day Case Surgery?

Does Intralipid Infusion Can Reverse the Spinal Anesthesia Effect in Day Case Surgery?

Not Recruiting
18-65 years
All
Phase N/A

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Overview

This study aims to evaluate the effect of intralipid infusion on reversing the spinal anesthesia effect in day case surgery.

Description

The increasing demand for day-case surgery has led to a growing interest in developing strategies to provide patients with a more convenient, cost-effective, and less invasive alternative to traditional inpatient procedures.

Spinal anesthesia, in particular, is a widely used technique in day-case surgery due to its ability to provide excellent analgesia with minimal side effects.

Intravenous lipid emulsion therapy is commonly used to treat local anesthetic systemic toxicity (LAST) and has demonstrated some efficacy in treating other drug toxicities, particularly cardiotoxicity from lipophilic drugs.

Eligibility

Inclusion Criteria:

  • Age from 18 to 65 years.
  • Both sexes.
  • American Society of Anesthesiology (ASA) physical status I-II.
  • Scheduled for day-case surgery under spinal anesthesia.
  • Time of surgery less than 90 min.

Exclusion Criteria:

  • Patients with contraindications for outpatient surgery or spinal anesthesia.
  • Local anaesthetic (LA) allergy.
  • Those receiving anticoagulant therapy.
  • Emergency cases.
  • Pregnant cases.

Study details
    Intralipid Infusion
    Spinal Anesthesia
    Day Case Surgery

NCT07025343

Benha University

12 December 2025

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